The contract value is £28m and represents the last major railway systems award under the project.
Under this contract, Knorr-Bremse will install the full-height platform screen doors at Paddington, Bond Street, Tottenham Court Road, Farringdon, Liverpool Street, Whitechapel, Canary Wharf and Woolwich Crossrail stations.
Crossrail programme director Simon Wright said: "Crossrail has now awarded the last of the major railway systems contracts. As major construction concludes, work will get underway to fit-out the new tunnels and stations with the necessary equipment and services to enable Crossrail services to operate.
"This will include the installation of over 40km of track, power equipment, as well as signalling, ventilation and drainage."
Design and development of the platform screen door system along with the manufacture of electronics and operating system will be performed at Melksham, Wiltshire, UK.
Assembling and testing of the system will take place at Knorr-Bremse ‘s Wolverton rail facility near Milton Keynes.
The 118km-long Crossrail route will serve 40 stations and run from Reading and Heathrow Airport in the west, through new twin-bore tunnels below central London to Shenfield and Abbey Wood in the east.
Once fully operational in 2019, Crossrail will boost rail capacity in London.